Mitochondrial tRNA^Leu(UUR) gene mutation and maternally inherited diabetes mellitus in Pakistani population

Electropherogram of Ethidium bromide stained 4% agarose gel for amplified 422 bp segment of mitochondrial DNA in control group. Lanes 1&2: patients with T2DM and deafness; lanes 3&4: patients with T2DM and no complaint of deafness; lanes 5&6: first-degree relatives of patients with T2DM and deafness group; lanes 7&8: non-diabetic controls.

Sequence alignment showing no A to G substitution at 3243 position in mtDNA of patient with T2DM & deafness.

Sequence alignment showing no A to G substitution at 3243 position in mtDNA of the first-degree relative of patient with T2DM & deafness.

Sequence alignment showing no A to G substitution at 3243 position in control group.